The Biochemical Journal, Volume 1

Couverture
Biochemical Society, 1906
Vols. 36-130 include Proceedings of the Biochemical Society for 1936-1972. These were superseded by the Society's Transactions in 1973.
 

Expressions et termes fréquents

Fréquemment cités

Page 28 - ON THE TREATMENT OF DIABETES MELLITUS BY ACID EXTRACT OF DUODENAL MUCOUS MEMBRANE BY BENJAMIN MOORE, MA, D.Sc., Johnston Professor of BioChemistry, University of Liverpool; EDWARD S.
Page 82 - Tincture of digitalis is less efficient as a cardiac stimulant (that is a drug which increases the cardiac output per beat) than squill, in that it has not the same effect in increasing the energy of contraction of the heart. Moreover, it is not possible by altering the relative dosage of digitalis to produce a stimulant effect in any way comparable to that of squill. Digitalis has less peripheral effect on the vagal mechanism than squill.
Page 160 - In order to maintain nitrogenous equilibrium, nitrogenous food stuffs must be ingested in such quantities, and in such form that the ammonia produced therefrom in the digestive tract is sufficient to maintain the intracellular alkalinity of the liver and probably other tissues. In order to fully understand this mechanism it is of importance here to consider the products other than nitrogenous bodies which are formed during autolysis.
Page 11 - A METHOD FOR DETERMINING THE TOTAL DAILY GAIN OR LOSS OF FIXED ALKALI, AND FOR ESTIMATING THE DAILY OUTPUT OF ORGANIC ACIDS IN THE URINE, WITH APPLICATIONS IN THE CASE OF DIABETES MELLITUS BY EDWARD S.
Page 444 - Moore's cases were of a kind similar to this one, and that the long latent period, which he attributed to secretin, belonged to the diet. There appears to us to be no sufficient evidence that secretin, when given by the mouth, can abolish or influence the glycosuria of severe diabetes. In the light of Starling's experience, that in animals secretin is not absorbed when introduced even in large amount into the alimentary canal, it seemed desirable to try the effect of full doses of secretin given...
Page 160 - ... acids, etc., which In their turn pass the alimentary tract, and by means of the metabolic processes there taking place liberate ammonia, which again inhibits the production of nitrogenous degradation products. Degradation of tissue should proceed, therefore, at a definite uniform rate. From the preliminary experiments carried out it seems that the production of acids is Inhibited by the presence of acids ; we have, therefore, a mechanism which tends to prevent excessive acidity or akalinity of...
Page 86 - WHITLEY, E. The Action of Acids and Alkalies, and of Acid, Alkaline, and Neutral Salts upon the Tadpole of Rana Temporaria.
Page 160 - The excess disappears gradually, however, if the animal is deprived of food. A certain stage will then be reached, when the production of acid exceeds the amount of ammonia available for neutralization ; the autolytic enzyme then comes into play, liberates amino-acids, etc., which in their turn pass the alimentary tract, and by means of the metabolic processes there taking place liberate ammonia, which again inhibits the production of nitrogenous degradation products.
Page 161 - The production of nitrogenous degradation products proceeds also at such a rate that there is never a dearth of nitrogenous bodies in the blood stream, and the bioplasm of the tissues, especially the mucous membrane of the small intestine, can remain saturated with side chains, for we have seen that the liver of a fasting animal contains more residual nitrogen than does that of a well-fed animal. " From these researches it follows that, while the animal derives most of its energy from the oxidation...

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